Only Good Antibodies — validation at a glance

Description

Highlights antibodies cited on a page and shows the knockout-controlled validation data for the application they were used in. Most antibodies in the literature have never been tested against a knockout. Only Good Antibodies marks the ones that have. Open a paper on a journal, preprint server or Europe PMC, and every antibody in the methods that YCharOS has independently tested is underlined in place, in the paper's own text. Hover it and you get the recommendation for each application — western blot, immunoprecipitation, immunofluorescence, flow cytometry — with the wild-type-versus-knockout image behind it, the clone, the RRID, and a link to the published report. Four states, because an antibody nobody has tested is not an antibody that failed: • Green — tested with knockout controls and recommended for this application. • Red — tested with knockout controls and not recommended for this application. Two antibodies in one sentence can differ, and often do. • Amber — the paper names a target but no catalogue number, or this exact product is not in the dataset. The extension says so plainly and points at the antibodies for that target that do have knockout-controlled data. • Grey — in the dataset, but never tested in this application. The recommendations come from YCharOS, an open-science consortium that characterises antibodies against knockout cell lines to a community consensus protocol and publishes every result, including the negative ones, as a peer-reviewed report with a DOI. Nothing here is a supplier claim or a citation count. How it handles your reading is the short part: matching happens entirely inside your browser. The extension downloads a small index of antibody records from onlygoodantibodies.co.uk once a day, and compares it against the text of the page you are on. Nothing about the page, the paper or you is transmitted anywhere — there is no account, no analytics, and no server that sees what you read. It works on around a hundred publisher, preprint and repository domains out of the box, and covers institutional proxies and supplier catalogue pages if you turn those on in settings. Free, and made by the people who generated the data.

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